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Excluded from randomized controlled trial (N = 295)
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Included in randomized controlled trial (N = 406)
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P value
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|---|
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Demographics and background
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Age (Mean ± SD), year
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65 ± 18
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66 ± 17
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0.411
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Gender (female)
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101 (34.2%)
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151 (37.2%)
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0.421
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Country
| | |
0.000
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Israel
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274 (92.9%)
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270 (66.5%)
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|
Greece
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16 (5.4%)
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76 (18.7%)
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Italy
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5 (1.7%)
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60 (14.8%)
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Admitted from home
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204 (69.2%)
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276 (68%)
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0.742
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BMI, kg/m2
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27.1 (6.7)
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27.4 (5.8)
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0.610
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Charlson Score (Mean ± SD)
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2 ± 2
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2 ± 2
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0.497
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Dementia
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17 (5.8%)
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49 (10.7%)
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0.050
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Diabetes
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61 (20.7%)
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90 (22.2%)
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0.636
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Chronic kidney disease
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71 (24.1%)
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79 (19.5%)
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0.129
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Hematological Malignancy
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25 (8.5%)
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14 (3.4%)
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0.004
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Congestive heart failure
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66 (22.4%)
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92 (22.7%)
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0.928
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Chronic pulmonary disease
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57 (19.3%)
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91 (22.4%)
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0.322
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Immune suppressive therapy
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54 (18.3%)
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61 (15%)
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0.247
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Known colonization by pathogen before infection
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69 (23.4%)
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96 (23.6%)
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0.937
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Recent surgery
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83 (28.1%)
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114 (28.1%)
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0.987
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Status at infection onset (culture taken time)
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Temperature, °C (SD)
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37.9 (1.7)
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38.0 (1.7)
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0.655
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Systolic blood pressure, mm Hg (SD)
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106 (24)
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109 (21)
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0.054
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Haemodynamic support
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68 (24.2%)
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75 (18.5%)
|
0.069
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Mechanical ventilation (invasive)
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198 (69.5%)
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264 (65%)
|
0.221
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Haemodialysis
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11 (3.9%)
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27 (6.7%)
|
0.118
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SOFA score (Mean ± SD)
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6 ± 3
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6 ± 3
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0.755
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Creatinine Clearance (Cockcroft-Gault Equation), mL/min (Percentiles 25–75)
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59.79 (32.54–108.58)
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69.95 (41.21–126.27)
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0.012
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Albumin, g/dL (SD)
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2.3 (0.6)
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2.4 (0.7)
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0.285
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White blood cells, thousands/mL (SD)
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13.22 (9.85)
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14.12 (8.89)
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0.212
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Arterial line
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76 (25.8%)
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151 (37.2%)
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0.001
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Central venous catheter
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119 (40.3%)
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225 (55.4%)
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0.000
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Urinary catheter
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228 (77.3%)
|
354 (87.2%)
|
0.001
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Nasogastric tube
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201 (68.1%)
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285 (70.2%)
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0.559
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