Excluded versus included patients in a randomized controlled trial of infections caused by carbapenem-resistant Gram-negative bacteria: relevance to external validity

Table 4 Logistic regression analysis of independent risk factors for clinical failure at day 14 of infection onset

	OR (95% CI)	P value
Exclusion from the RCT	1.341 (0.818–2.200)	0.245
Age^a	1.018 (1.005–1.031)	0.006
Gender (female)	0.543 (0.345–0.854)	0.008
Enterobacterales	0.658 (0.361–1.202)	0.173
Pseudomonas/other	0.416 (0.183–0.416)	0.037
Systolic blood pressure, mm Hg^b	0.992 (0.981–1.002)	0.119
Haemodynamic support	2.561 (1.188–5.520)	0.016
Mechanical ventilation (invasive)	1.481 (0.920–2.384)	0.106
Acquisition of infection in the intensive care unit	2.061 (1.170–3.632)	0.012

N = 701Akaike’s information criterion goodness of fit = 516.012; constant: β = 2.311; risk for clinical failure at day 14: OR > 1
^aAge- per 1 year increment
^bSystolic blood pressure - per 1 mm Hg increment

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