Fig. 2

The MIC distribution of FOS in monotherapy or combination with TGC or CMS against 136 KPC-producing. Klebsiella pneumoniae, and probability of target attainment (PTA) of 24 AUC24/MIC for FOS dosing regimens in critically. Ill elderly patients with normal renal function (Left) and renal impairment (right). The dotted line indicates the PTA of 0.9. FOS, fosfomycin; TGC, tigecycline; CST, colistin